New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs.

Eitemau Tebyg

• An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives.
  gan: Debyser, Z, et al.
  Cyhoeddwyd: (1991)
• Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro.
  gan: Baba, M, et al.
  Cyhoeddwyd: (1987)
• Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs.
  gan: Thormar, H, et al.
  Cyhoeddwyd: (1993)
• Specific interaction of aurintricarboxylic acid with the human immunodeficiency virus/CD4 cell receptor.
  gan: Schols, D, et al.
  Cyhoeddwyd: (1989)
• Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase.
  gan: Pauwels, R, et al.
  Cyhoeddwyd: (1993)