Загрузка...
Functional interaction between S1 and S4 segments in voltage-gated sodium channels revealed by human channelopathies
The p.I141V mutation of the voltage-gated sodium channel is associated with several clinical hyper-excitability phenotypes. To understand the structural bases of the p.I141V biophysical alterations, molecular dynamics simulations were performed. These simulations predicted that the p.I141V substitut...
Сохранить в:
| Опубликовано в: : | Channels (Austin) |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594541/ https://ncbi.nlm.nih.gov/pubmed/25483584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336950.2014.958922 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|