A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.

Sequence-specific DNA binding has been demonstrated for a synthetic peptide comprising only one of the two "finger"-like domains of the erythroid transcription factor GATA-1 (also termed Eryf-1, NF-E1, or GF-1). Quantitative analysis of gel-retardation assays yields a specific association...

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Bibliographische Detailangaben
Hauptverfasser: Omichinski, J G, Trainor, C, Evans, T, Gronenborn, A M, Clore, G M, Felsenfeld, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45942/
https://ncbi.nlm.nih.gov/pubmed/8446581
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