A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.

Sequence-specific DNA binding has been demonstrated for a synthetic peptide comprising only one of the two "finger"-like domains of the erythroid transcription factor GATA-1 (also termed Eryf-1, NF-E1, or GF-1). Quantitative analysis of gel-retardation assays yields a specific association constant o...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Omichinski, J G, Trainor, C, Evans, T, Gronenborn, A M, Clore, G M, Felsenfeld, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8446581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.5.1676
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