The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high-affinity specific DNA binding.

Specific DNA binding to the core consensus site GAGAGAG has been shown with an 82-residue peptide (residues 310-391) taken from the Drosophila transcription factor GAGA. Using a series of deletion mutants, it was demonstrated that the minimal domain required for specific binding (residues 310-372) i...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Pedone, P V, Ghirlando, R, Clore, G M, Gronenborn, A M, Felsenfeld, G, Omichinski, J G
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1996
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8610125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.7.2822
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