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High resolution structure of an M23 peptidase with a substrate analogue

LytM is a Staphylococcus aureus autolysin and a homologue of the S. simulans lysostaphin. Both enzymes are members of M23 metallopeptidase family (MEROPS) comprising primarily bacterial peptidoglycan hydrolases. LytM occurs naturally in a latent form, but can be activated by cleavage of an inhibitor...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Grabowska, Maja, Jagielska, Elzbieta, Czapinska, Honorata, Bochtler, Matthias, Sabala, Izabela
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594094/
https://ncbi.nlm.nih.gov/pubmed/26437833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14833
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