Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans

Staphylococcus simulans biovar staphylolyticus lysostaphin efficiently cleaves Staphylococcus aureus cell walls. The protein is in late clinical trials as a topical anti-staphylococcal agent, and can be used to prevent staphylococcal growth on artificial surfaces. Moreover, the gene has been both st...

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Vydáno v:FEBS J
Hlavní autoři: Sabala, Izabela, Jagielska, Elzbieta, Bardelang, Philip T, Czapinska, Honorata, Dahms, Sven O, Sharpe, Jason A, James, Richard, Than, Manuel E, Thomas, Neil R, Bochtler, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Implications for Medicine and Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286107/
https://ncbi.nlm.nih.gov/pubmed/25039253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12929
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