N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens

BACKGROUND: The temporary or long-term xenotransplantation of pig organs into people would save thousands of lives each year if not for the robust human antibody response to pig carbohydrates. Genetically engineered pigs deficient in galactose α1,3 galactose (gene modified: GGTA1) and N-glycolylneur...

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Bibliografiska uppgifter
I publikationen:Xenotransplantation
Huvudupphovsmän: Burlak, Christopher, Bern, Marshall, Brito, Alejandro E., Isailovic, Dragan, Wang, Zheng-Yu, Estrada, Jose L., Li, Ping, Tector, A. Joseph
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593510/
https://ncbi.nlm.nih.gov/pubmed/24033743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12047
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