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Erythrocytes from GGTA1/CMAH knockout pigs: implications for xenotransfusion and testing in non-human primates

BACKGROUND: Pig erythrocytes are potentially useful to solve the worldwide shortage of human blood for transfusion. Domestic pig erythrocytes, however, express antigens that are bound by human preformed antibodies. Advances in genetic engineering have made it possible to rapidly knock out the genes...

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Detalhes bibliográficos
Publicado no:Xenotransplantation
Main Authors: Wang, Zheng-Yu, Burlak, Christopher, Estrada, Jose L., Li, Ping, Tector, Matthew F., Tector, A. Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366650/
https://ncbi.nlm.nih.gov/pubmed/24986655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12106
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