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Erythrocytes from GGTA1/CMAH knockout pigs: implications for xenotransfusion and testing in non-human primates

BACKGROUND: Pig erythrocytes are potentially useful to solve the worldwide shortage of human blood for transfusion. Domestic pig erythrocytes, however, express antigens that are bound by human preformed antibodies. Advances in genetic engineering have made it possible to rapidly knock out the genes...

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Podrobná bibliografie
Vydáno v:Xenotransplantation
Hlavní autoři: Wang, Zheng-Yu, Burlak, Christopher, Estrada, Jose L., Li, Ping, Tector, Matthew F., Tector, A. Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366650/
https://ncbi.nlm.nih.gov/pubmed/24986655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12106
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