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PoLi: A Virtual Screening Pipeline Based On Template Pocket And Ligand Similarity

Often in pharmaceutical research, the goal is to identify small molecules that can interact with and appropriately modify the biological behavior of a new protein target. Unfortunately, most proteins lack both known structures and small molecule binders, prerequisites of many virtual screening, VS,...

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Dades bibliogràfiques
Publicat a:J Chem Inf Model
Autors principals: Roy, Ambrish, Srinivasan, Bharath, Skolnick, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593500/
https://ncbi.nlm.nih.gov/pubmed/26225536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00232
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