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PoLi: A Virtual Screening Pipeline Based On Template Pocket And Ligand Similarity

Often in pharmaceutical research, the goal is to identify small molecules that can interact with and appropriately modify the biological behavior of a new protein target. Unfortunately, most proteins lack both known structures and small molecule binders, prerequisites of many virtual screening, VS,...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Chem Inf Model
Главные авторы: Roy, Ambrish, Srinivasan, Bharath, Skolnick, Jeffrey
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593500/
https://ncbi.nlm.nih.gov/pubmed/26225536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00232
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