Structural analysis of tumor-related single amino acid mutations in human MxA protein

BACKGROUND: Human myxovirus resistant protein A (MxA), encoded by the myxovirus resistance 1 (Mx1) gene, is an interferon (IFN)-triggered dynamin-like multi-domain GTPase involved in innate immune responses against viral infections. Recent studies suggest that MxA is associated with several human ca...

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Publicado no:Chin J Cancer
Main Authors: Hu, Jia-Li, Hua, Yi-Jun, Chen, Yang, Yu, Bing, Gao, Song
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593380/
https://ncbi.nlm.nih.gov/pubmed/26411585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-015-0055-1
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https://ncbi.nlm.nih.gov/pmc/articles/PMC4593380/
https://ncbi.nlm.nih.gov/pubmed/26411585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-015-0055-1