Cargando...
DNA Ligase I Is Not Essential for Mammalian Cell Viability
Of the three DNA ligases present in all vertebrates, DNA ligase I (Lig1) has been considered essential for ligating Okazaki fragments during DNA replication and thereby essential for cell viability. Here, we report the striking finding that a Lig1-null murine B cell line is viable. Surprisingly, the...
Guardado en:
| Publicado en: | Cell Rep |
|---|---|
| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593317/ https://ncbi.nlm.nih.gov/pubmed/24726358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.024 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|