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CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex
A key point to regulate gene expression is at transcription initiation, and activators play a major role. CarD, an essential activator in Mycobacterium tuberculosis, is found in many bacteria, including Thermus species, but absent in Escherichia coli. To delineate the molecular mechanism of CarD, we...
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| Pubblicato in: | eLife |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593161/ https://ncbi.nlm.nih.gov/pubmed/26349034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08505 |
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