Structure and function of CarD, an essential mycobacterial transcription factor

CarD, an essential transcription regulator in Mycobacterium tuberculosis, directly interacts with the RNA polymerase (RNAP). We used a combination of in vivo and in vitro approaches to establish that CarD is a global regulator that stimulates the formation of RNAP-holoenzyme open promoter (RPo) comp...

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Main Authors: Srivastava, Devendra B., Leon, Katherine, Osmundson, Joseph, Garner, Ashley L., Weiss, Leslie A., Westblade, Lars F., Glickman, Michael S., Landick, Robert, Darst, Seth A., Stallings, Christina L., Campbell, Elizabeth A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732983/
https://ncbi.nlm.nih.gov/pubmed/23858468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308270110
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