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CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism
CarD is an essential and global transcriptional regulator in mycobacteria. While its biological role is unclear, CarD functions by interacting directly with RNA polymerase (RNAP) holoenzyme promoter complexes. Here, using a fluorescent reporter of open complex, we quantitate RP(o) formation in real...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381055/ https://ncbi.nlm.nih.gov/pubmed/25697505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv078 |
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