Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest

T lymphocytes are highly motile cells that decelerate upon antigen recognition. These cells can either completely stop or maintain a low level of motility, forming contacts referred to as synapses or kinapses, respectively. Whether similar or distinct molecular mechanisms regulate T-cell deceleratio...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Moreau, Hélène D., Lemaître, Fabrice, Garrod, Kym R., Garcia, Zacarias, Lennon-Duménil, Ana-Maria, Bousso, Philippe
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593123/
https://ncbi.nlm.nih.gov/pubmed/26371316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506654112
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