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Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division

T cells are primed in secondary lymphoid organs by establishing stable interactions with antigen-presenting cells (APCs). However, the cellular mechanisms underlying the termination of T cell priming and the initiation of clonal expansion remain largely unknown. Using intravital imaging, we observed...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Bohineust, Armelle, Garcia, Zacarias, Beuneu, Hélène, Lemaître, Fabrice, Bousso, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940264/
https://ncbi.nlm.nih.gov/pubmed/29588347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171708
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