SPG7 is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore

Mitochondrial permeability transition is a phenomenon in which the mitochondrial permeability transition pore (PTP) abruptly opens resulting in mitochondrial membrane potential (ΔΨ(m)) dissipation, loss of ATP production, and cell death. Several genetic candidates have been proposed to form the PTP...

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Publicado no:Mol Cell
Main Authors: Shanmughapriya, Santhanam, Rajan, Sudarsan, Hoffman, Nicholas E., Higgins, Andrew M., Tomar, Dhanendra, Nemani, Neeharika, Hines, Kevin J., Smith, Dylan J., Eguchi, Akito, Vallem, Sandhya, Shaikh, Farah, Cheung, Maggie, Leonard, Nicole J., Stolakis, Ryan S., Wolfers, Matthew P., Ibetti, Jessica, Chuprun, J. Kurt, Jog, Neelakshi R., Houser, Steven R., Koch, Walter J., Elrod, John W., Madesh, Muniswamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592475/
https://ncbi.nlm.nih.gov/pubmed/26387735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.08.009
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