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The MYC–WDR5 Nexus and Cancer

The MYC oncogenes encode a family of transcription factors that feature prominently in cancer. MYC proteins are overexpressed or deregulated in a majority of malignancies, and drive tumorigenesis by inducing widespread transcriptional reprogramming that promotes cell proliferation, metabolism, and g...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Tansey, William P.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592407/
https://ncbi.nlm.nih.gov/pubmed/26383167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1216
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