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Rodent models for Alzheimer’s disease drug discovery
INTRODUCTION: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by memory loss and personality changes, leading to dementia. Histophatological hallmarks are represented by aggregates of beta-amyloid peptide (Aβ) in senile plaques and deposition of hyperphosphorylated tau protein...
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| Publié dans: | Expert Opin Drug Discov |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592281/ https://ncbi.nlm.nih.gov/pubmed/25927677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2015.1041913 |
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