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Development of DENVax: A chimeric dengue-2 PDK-53-based tetravalent vaccine for protection against dengue fever

Dengue. virus infection is the leading arboviral cause of disease worldwide. A vaccine is being developed based on the attenuated DEN-2 virus, DEN-2 PDK-53. In this review, we summarize the characteristics of the parent DEN-2 PDK-53 strain as well as the chimeric viruses containing the prM and E gen...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Osorio, Jorge E., Huang, Claire Y.-H., Kinney, Richard M., Stinchcomb, Dan T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592106/
https://ncbi.nlm.nih.gov/pubmed/21777638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.07.020
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