Φορτώνει......
FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2
The Fanconi anemia (FA)-BRCA pathway mediates repair of DNA interstrand crosslinks. The FA core complex, a multi-subunit ubiquitin ligase, participates in the detection of DNA lesions and monoubiquitinates two downstream FA proteins, FANCD2 and FANCI (or the ID complex). However, the regulation of t...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | PLoS Genet |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592014/ https://ncbi.nlm.nih.gov/pubmed/26430909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005563 |
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