Targeting the WNT Signaling Pathway in Cancer Therapeutics

The WNT signaling cascade is integral in numerous biological processes including embryonic development, cell cycle regulation, inflammation, and cancer. Hyperactivation of WNT signaling secondary to alterations to varying nodes of the pathway have been identified in multiple tumor types. These alter...

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Vydáno v:Oncologist
Hlavní autoři: Tai, David, Wells, Keith, Arcaroli, John, Vanderbilt, Chad, Aisner, Dara L., Messersmith, Wells A., Lieu, Christopher H.
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2015
Témata:
New Drug Development and Clinical Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591954/
https://ncbi.nlm.nih.gov/pubmed/26306903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0057
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