Targeting the WNT Signaling Pathway in Cancer Therapeutics

The WNT signaling cascade is integral in numerous biological processes including embryonic development, cell cycle regulation, inflammation, and cancer. Hyperactivation of WNT signaling secondary to alterations to varying nodes of the pathway have been identified in multiple tumor types. These alter...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Tai, David, Wells, Keith, Arcaroli, John, Vanderbilt, Chad, Aisner, Dara L., Messersmith, Wells A., Lieu, Christopher H.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2015
Assuntos:
New Drug Development and Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591954/
https://ncbi.nlm.nih.gov/pubmed/26306903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0057
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