Targeting the WNT Signaling Pathway in Cancer Therapeutics

The WNT signaling cascade is integral in numerous biological processes including embryonic development, cell cycle regulation, inflammation, and cancer. Hyperactivation of WNT signaling secondary to alterations to varying nodes of the pathway have been identified in multiple tumor types. These alter...

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Bibliografische gegevens
Gepubliceerd in:Oncologist
Hoofdauteurs: Tai, David, Wells, Keith, Arcaroli, John, Vanderbilt, Chad, Aisner, Dara L., Messersmith, Wells A., Lieu, Christopher H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AlphaMed Press 2015
Onderwerpen:
New Drug Development and Clinical Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591954/
https://ncbi.nlm.nih.gov/pubmed/26306903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0057
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