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Saturated Fatty Acids Induce Post-transcriptional Regulation of HAMP mRNA via AU-rich Element-binding Protein, Human Antigen R (HuR)

Iron is implicated in fatty liver disease pathogenesis. The human hepcidin gene, HAMP, is the master switch of iron metabolism. The aim of this study is to investigate the regulation of HAMP expression by fatty acids in HepG2 cells. For these studies, both saturated fatty acids (palmitic acid (PA) a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Lu, Sizhao, Mott, Justin L., Harrison-Findik, Duygu Dee
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591806/
https://ncbi.nlm.nih.gov/pubmed/26304124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.648212
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