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Epidermal growth factor–stimulated Akt phosphorylation requires clathrin or ErbB2 but not receptor endocytosis

Epidermal growth factor (EGF) binding to its receptor (EGFR) activates several signaling intermediates, including Akt, leading to control of cell survival and metabolism. Concomitantly, ligand-bound EGFR is incorporated into clathrin-coated pits—membrane structures containing clathrin and other prot...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Biol Cell
Päätekijät: Garay, Camilo, Judge, Gurjeet, Lucarelli, Stefanie, Bautista, Stephen, Pandey, Rohan, Singh, Tanveer, Antonescu, Costin N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591694/
https://ncbi.nlm.nih.gov/pubmed/26246598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-09-1412
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