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THE KEYSTONE OF ALZHEIMER PATHOGENESIS MIGHT BE SOUGHT IN Aβ PHYSIOLOGY
For several years Amyloid-beta peptide (Aβ) has been considered the main pathogenetic factor of Alzheimer's disease (AD). According to the so called Amyloid Cascade Hypothesis the increase of Aβ triggers a series of events leading to synaptic dysfunction and memory loss as well as to the struct...
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| Published in: | Neuroscience |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4591241/ https://ncbi.nlm.nih.gov/pubmed/26314631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.08.039 |
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