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p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing
We have recently shown that E1A protein of human adenovirus downregulates epidermal growth factor receptor (EGFR) expression and induces apoptosis in head and neck (HNSCC) and lung cancer cells independently of their p53 status. E1A has five isoforms of which the major ones E1A12S and E1A13S regulat...
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| Publicat a: | Oncogene |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4591001/ https://ncbi.nlm.nih.gov/pubmed/17486071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210497 |
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