PML involvement in the p73-mediated E1A-induced suppression of EGFR and induction of apoptosis in head and neck cancers

Epidermal growth factor receptor (EGFR) tyrosine kinase is commonly overexpressed in human cancers; however, the cellular mechanisms regulating EGFR expression remain unclear. p53, p63 and p73 are transcription factors regulating many cellular targets involved in controlling the cell cycle and apopt...

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Detalhes bibliográficos
Main Authors: Klanrit, P, Taebunpakul, P, Flinterman, MB, Odell, EW, Riaz, MA, Melino, G, Salomoni, P, Mymryk, JS, Gäken, J, Farzaneh, F, Tavassoli, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882231/
https://ncbi.nlm.nih.gov/pubmed/19597475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.191
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