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Programming cells by multiplex genome engineering and accelerated evolution
The breadth of genomic diversity found among organisms in nature allows populations to adapt to diverse environments(1,2). However, genomic diversity is difficult to generate in the laboratory and new phenotypes do not easily arise on practical timescales(3). Although in vitro and directed evolution...
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| Publicat a: | Nature |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4590770/ https://ncbi.nlm.nih.gov/pubmed/19633652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08187 |
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