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Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

Genome-scale engineering of living organisms requires precise and economical methods to efficiently modify many loci within chromosomes. One such example is the directed integration of chemically synthesized single-stranded deoxyribonucleic acid (oligonucleotides) into the chromosome of Escherichia...

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Detalhes bibliográficos
Main Authors: Carr, Peter A., Wang, Harris H., Sterling, Bram, Isaacs, Farren J., Lajoie, Marc J., Xu, George, Church, George M., Jacobson, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458525/
https://ncbi.nlm.nih.gov/pubmed/22638574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks455
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