Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves’ ophthalmopathy and Hashimoto’s thyroiditis

BACKGROUND: The eye disorder associated with Graves’ disease, called Graves’ ophthalmopathy (GO), greatly reduces the quality of life in affected patients. Expression of the calsequestrin (CASQ1) protein in thyroid tissue may be the trigger for the development of eye muscle damage in patients with G...

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Veröffentlicht in:Clin Ophthalmol
Hauptverfasser: Lahooti, Hooshang, Cultrone, Daniele, Edirimanne, Senarath, Walsh, John P, Delbridge, Leigh, Cregan, Patrick, Champion, Bernard, Wall, Jack R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590686/
https://ncbi.nlm.nih.gov/pubmed/26445519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S87972
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