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Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves’ ophthalmopathy and Hashimoto’s thyroiditis

BACKGROUND: The eye disorder associated with Graves’ disease, called Graves’ ophthalmopathy (GO), greatly reduces the quality of life in affected patients. Expression of the calsequestrin (CASQ1) protein in thyroid tissue may be the trigger for the development of eye muscle damage in patients with G...

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Bibliografiske detaljer
Udgivet i:Clin Ophthalmol
Main Authors: Lahooti, Hooshang, Cultrone, Daniele, Edirimanne, Senarath, Walsh, John P, Delbridge, Leigh, Cregan, Patrick, Champion, Bernard, Wall, Jack R
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590686/
https://ncbi.nlm.nih.gov/pubmed/26445519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S87972
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