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Single nucleotide polymorphism 1623 A/G (rs180195) in the promoter of the Thyroglobulin gene is associated with autoimmune thyroid disease but not with thyroid ophthalmopathy

BACKGROUND: Our studies over recent years have focused on some new ideas concerning the pathogenesis for the orbital reaction that characterizes Graves’ ophthalmopathy namely, that there are antigens expressed by thyroid tissue and orbital tissue where they are targeted by autoantibodies and/or sens...

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Detalles Bibliográficos
Publicado en:Clin Ophthalmol
Main Authors: Lahooti, Hooshang, Edirimanne, Senarath, Walsh, John P, Delbridge, Leigh, Hibbert, Emily J, Wall, Jack R
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536092/
https://ncbi.nlm.nih.gov/pubmed/28794611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S136070
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