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Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves’ ophthalmopathy and Hashimoto’s thyroiditis

BACKGROUND: The eye disorder associated with Graves’ disease, called Graves’ ophthalmopathy (GO), greatly reduces the quality of life in affected patients. Expression of the calsequestrin (CASQ1) protein in thyroid tissue may be the trigger for the development of eye muscle damage in patients with G...

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Dettagli Bibliografici
Pubblicato in:Clin Ophthalmol
Autori principali: Lahooti, Hooshang, Cultrone, Daniele, Edirimanne, Senarath, Walsh, John P, Delbridge, Leigh, Cregan, Patrick, Champion, Bernard, Wall, Jack R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590686/
https://ncbi.nlm.nih.gov/pubmed/26445519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S87972
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