Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

Lysosomal membrane permeabilization (LMP) contributes to tissue involution, degenerative diseases, and cancer therapy. Its investigation has, however, been hindered by the lack of sensitive methods. Here, we characterize and validate the detection of galectin puncta at leaky lysosomes as a highly se...

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Publicat a:Autophagy
Autors principals: Aits, Sonja, Kricker, Jennifer, Liu, Bin, Ellegaard, Anne-Marie, Hämälistö, Saara, Tvingsholm, Siri, Corcelle-Termeau, Elisabeth, Høgh, Søren, Farkas, Thomas, Holm Jonassen, Anna, Gromova, Irina, Mortensen, Monika, Jäättelä, Marja
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590643/
https://ncbi.nlm.nih.gov/pubmed/26114578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1063871
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