Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

Lysosomal membrane permeabilization (LMP) contributes to tissue involution, degenerative diseases, and cancer therapy. Its investigation has, however, been hindered by the lack of sensitive methods. Here, we characterize and validate the detection of galectin puncta at leaky lysosomes as a highly se...

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Pubblicato in:Autophagy
Autori principali: Aits, Sonja, Kricker, Jennifer, Liu, Bin, Ellegaard, Anne-Marie, Hämälistö, Saara, Tvingsholm, Siri, Corcelle-Termeau, Elisabeth, Høgh, Søren, Farkas, Thomas, Holm Jonassen, Anna, Gromova, Irina, Mortensen, Monika, Jäättelä, Marja
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590643/
https://ncbi.nlm.nih.gov/pubmed/26114578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1063871
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