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Bioinspired genotype–phenotype linkages: mimicking cellular compartmentalization for the engineering of functional proteins

The idea of compartmentalization of genotype and phenotype in cells is key for enabling Darwinian evolution. This contribution describes bioinspired systems that use in vitro compartments—water-in-oil droplets and gel-shell beads—for the directed evolution of functional proteins. Technologies based...

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Detalhes bibliográficos
Publicado no:Interface Focus
Main Authors: van Vliet, Liisa D., Colin, Pierre-Yves, Hollfelder, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590426/
https://ncbi.nlm.nih.gov/pubmed/26464791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2015.0035
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