Increased sMICA and TGFβ(1) levels in HNSCC patients impair NKG2D-dependent functionality of activated NK cells

Disseminated head-and-neck squamous cell carcinoma (HNSCC) escapes immune surveillance and thus frequently manifests as fatal disease. Here, we report on the distribution of distinct immune cell subpopulations, natural killer (NK) cell cytotoxicity and tumor immune escape mechanisms (TIEMs) in 55 HN...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Klöß, Stephan, Chambron, Nicole, Gardlowski, Tanja, Arseniev, Lubomir, Koch, Joachim, Esser, Ruth, Glienke, Wolfgang, Seitz, Oliver, Köhl, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589991/
https://ncbi.nlm.nih.gov/pubmed/26451327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1055993
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