Cetuximab Reconstitutes Pro-Inflammatory Cytokine Secretions and Tumor-Infiltrating Capabilities of sMICA-Inhibited NK Cells in HNSCC Tumor Spheroids

Immunosuppressive factors, such as soluble major histocompatibility complex class I chain-related peptide A (sMICA) and transforming growth factor beta 1 (TGF-β(1)), are involved in tumor immune escape mechanisms (TIEMs) exhibited by head and neck squamous cell carcinomas (HNSCCs) and may represent...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Klöss, Stephan, Chambron, Nicole, Gardlowski, Tanja, Weil, Sandra, Koch, Joachim, Esser, Ruth, Pogge von Strandmann, Elke, Morgan, Michael A., Arseniev, Lubomir, Seitz, Oliver, Köhl, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629470/
https://ncbi.nlm.nih.gov/pubmed/26579120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00543
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