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Plasma Chemokine signature correlates with lung goblet cell hyperplasia in smokers with and without chronic obstructive pulmonary disease

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is characterized by lung and systemic inflammation as well as airway goblet cell hyperplasia (GCH). Mucin production is activated in part by stimulation of the epidermal growth factor (EGF) receptor pathway through neutrophils and macrophages....

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Publicado en:BMC Pulm Med
Autores principales: Kim, Victor, Cornwell, William D., Oros, Michelle, Durra, Heba, Criner, Gerard J., Rogers, Thomas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589974/
https://ncbi.nlm.nih.gov/pubmed/26424214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0103-2
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