Plasma Chemokine signature correlates with lung goblet cell hyperplasia in smokers with and without chronic obstructive pulmonary disease

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is characterized by lung and systemic inflammation as well as airway goblet cell hyperplasia (GCH). Mucin production is activated in part by stimulation of the epidermal growth factor (EGF) receptor pathway through neutrophils and macrophages....

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Vydáno v:BMC Pulm Med
Hlavní autoři: Kim, Victor, Cornwell, William D., Oros, Michelle, Durra, Heba, Criner, Gerard J., Rogers, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589974/
https://ncbi.nlm.nih.gov/pubmed/26424214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0103-2
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