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New Concepts in the Pathobiology of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is characterized by an abnormal persistent inflammatory response to cigarette smoke. This noxious insult leads to emphysema and airway remodeling, manifested by squamous and mucous metaplasia of the epithelium, smooth muscle hypertrophy, and airway wall f...

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Bibliographic Details
Main Authors: Kim, Victor, Rogers, Thomas J., Criner, Gerard J.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645323/
https://ncbi.nlm.nih.gov/pubmed/18453359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200802-014ET
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