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Plasma Chemokine signature correlates with lung goblet cell hyperplasia in smokers with and without chronic obstructive pulmonary disease

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is characterized by lung and systemic inflammation as well as airway goblet cell hyperplasia (GCH). Mucin production is activated in part by stimulation of the epidermal growth factor (EGF) receptor pathway through neutrophils and macrophages....

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Détails bibliographiques
Publié dans:BMC Pulm Med
Auteurs principaux: Kim, Victor, Cornwell, William D., Oros, Michelle, Durra, Heba, Criner, Gerard J., Rogers, Thomas J.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589974/
https://ncbi.nlm.nih.gov/pubmed/26424214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0103-2
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