Plasma Chemokine signature correlates with lung goblet cell hyperplasia in smokers with and without chronic obstructive pulmonary disease

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is characterized by lung and systemic inflammation as well as airway goblet cell hyperplasia (GCH). Mucin production is activated in part by stimulation of the epidermal growth factor (EGF) receptor pathway through neutrophils and macrophages....

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Bibliographic Details
Published in:BMC Pulm Med
Main Authors: Kim, Victor, Cornwell, William D., Oros, Michelle, Durra, Heba, Criner, Gerard J., Rogers, Thomas J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589974/
https://ncbi.nlm.nih.gov/pubmed/26424214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0103-2
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