Sporadic Creutzfeldt-Jakob Disease: Prion Pathology in Medulla Oblongata—Possible Routes of Infection and Host Susceptibility

Sporadic Creutzfeldt-Jakob disease (sCJD), the most frequent human prion disorder, is characterized by remarkable phenotypic variability, which is influenced by the conformation of the pathologic prion protein and the methionine/valine polymorphic codon 129 of the prion protein gene. While the etiol...

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Bibliographic Details
Published in:Biomed Res Int
Main Authors: Iacono, Diego, Ferrari, Sergio, Gelati, Matteo, Zanusso, Gianluigi, Mariotto, Sara, Monaco, Salvatore
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589575/
https://ncbi.nlm.nih.gov/pubmed/26457299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/396791
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