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Alternative splicing of the cell-fate determinant Numb in hepatocellular carcinoma

BACKGROUND: The cell fate determinant Numb is aberrantly expressed in cancer. Numb is alternatively spliced with one isoform containing an extended proline rich region (PRR(L)) compared to the other (PRR(S)). PRR(L) was recently reported to enhance proliferation of breast and lung cancer cells. Howe...

詳細記述

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書誌詳細
出版年:Hepatology
主要な著者: Lu, Yin Ying, Xu, Wanping, Ji, Junfang, Feng, Dechun, Sourbier, Carole, Yang, Youfeng, Qu, Jianhui, Zeng, Zhen, Wang, Chunping, Chang, Xiujuan, Chen, Yan, Mishra, Alok, Xu, Max, Lee, Min-Jung, Lee, Sunmin, Trepel, Jane, Linehan, W. Marston, Wang, Xin Wei, Yang, Yongping, Neckers, Len
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589429/
https://ncbi.nlm.nih.gov/pubmed/26058814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27923
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