Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene.
We have identified a functional silencer element (positions -231 to -211) in the human synapsin I gene that selectively represses its transcription in nonneuronal cells. Transfection experiments using synapsin I-luciferase constructs show that site-specific mutations or deletion of this silencer seq...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8381968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1460 |
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