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Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfinding errors in vivo

The neuron-restrictive silencer factor (NRSF; also known as REST for repressor element-1 silencing transcription factor) is a transcriptional repressor of multiple neuronal genes, but little is known about its function in vivo. NRSF is normally down-regulated upon neuronal differentiation. Constitut...

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Hlavní autoři: Paquette, Alice J., Perez, Sharon E., Anderson, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC17339/
https://ncbi.nlm.nih.gov/pubmed/11050251
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