Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfinding errors in vivo

The neuron-restrictive silencer factor (NRSF; also known as REST for repressor element-1 silencing transcription factor) is a transcriptional repressor of multiple neuronal genes, but little is known about its function in vivo. NRSF is normally down-regulated upon neuronal differentiation. Constitut...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Paquette, Alice J., Perez, Sharon E., Anderson, David J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2000
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050251/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.22.12318
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