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Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene.

We have identified a functional silencer element (positions -231 to -211) in the human synapsin I gene that selectively represses its transcription in nonneuronal cells. Transfection experiments using synapsin I-luciferase constructs show that site-specific mutations or deletion of this silencer seq...

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Autors principals: Li, L, Suzuki, T, Mori, N, Greengard, P
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC45893/
https://ncbi.nlm.nih.gov/pubmed/8381968
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